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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc9278a88d916ac60c480f3435e07332e355a6019ddedc7a51dfd5c7313fec27' 
  AND token = 'd3Q6A/1ddz5QSzfC/I3LaKkv2A/jxRV+dRrEoftIFqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}