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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7ce378e03d07593a4b447686af177f64d5075a54f41834ee6b15f3693c69f7' 
  AND token = 'O53I7krhl9XXjiQc5HLeCaULqe1qNFpBjj+qmDRfl1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}