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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39717a28edf9b6210dfac8e5d59361206b16bcebcb27677e2d92a3c2047778b9' 
  AND token = 'fZFtDgUG2RN4vebk4bX8+Goy8NM0iP9Ln8Mo3cl+EIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}