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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bea81452fe052d80e2f2009b956cc6d62e81b37a7f81bca3f0f3701147dabf25' 
  AND token = 'LWl/KJQ0/pYnZCb7d1actFdT+UX1yecB8QD35fM6kfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}