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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb689d2501369b0f280a609b082f94716fc6e7c096e4e82e2d0a27ada9f88190' 
  AND token = 'tn2FmL0Ttma6UHCs4PvXKouBqi+fABcPe7i9rPW7luI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}