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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d6699ce15b187172f8cab76fddcbcb81aae2822aa2634d2ec96e3ccfb3fa259' 
  AND token = '2Md07bTi4INfAIFw5yT4GE2HcyjhIQqsOE9h2SfefSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}