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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a42b15ec123cf47208519eff0ecd628ae95650c84adec1907137c773e99f5af4' 
  AND token = 'sKR41+GWGCoNaj57xZUiAJzJBb3bkRm3QiaRRayDbhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}