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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd66edc89d6ad77d21ccf8bf6c620898a20a7685259734475f5bd4b0a07369155' 
  AND token = '1ibIMsQFkGN4KPk625nRitlRnUslVLAnIw+gBjpgVtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}