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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01260e7a8760a0fb14540d94051f8e8d3116a00335c9bfd68618bf46a7b9a0fd' 
  AND token = 'bF6NH1y+aoWJL7c5Am5gQFmKpWzf/LLLKk7mL5+HDew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}