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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7d12cc322d3928686e9cd67079a6f05ae779b7810b175e2f53e564b9d6e7559' 
  AND token = 'xytm5AZh/fwIto2bnjtljy5ksqz7yPnEDbJh++Gw3UA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}