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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227bb9a82409fc02c80f9fa639d07527c4b455492593d942478d72d347ccc158' 
  AND token = '64KxYAvll/GM12XXT97fUTzLFfFuHlk5pmlY8gApRJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}