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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21565e13675e1acf5e29bb25c037e5ae2f034a29912c32344703d4febde6b334' 
  AND token = 'mr8zRzfhi8glc30MVzinKdUQ/XrvkkPggsiyXPmLKJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}