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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a97bd5221ad03a620139404671fde7d8c3992c12419a5ca51fc59ea259bce6cd' 
  AND token = 'PyjkaKTKYlHS/XPu6VoS+r8Nu4weAK9reK8gw3DrLmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}