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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b343cae6992827cd1e6817d33b86ac334e892e2a70021ad9b66a70ca6d9eefd' 
  AND token = 'tCfjz5vD3jtX2xRRAsa/Aa2nZylstc5ucEmkjYy8bhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}