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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78907767fbe82b7648613e0bbdab8b2916dd1da9a33d2697deb2d452699896e8' 
  AND token = 'y+0hV2wp/q8uo9y+XCX9ZNHj94hC65i1j4JafyafY/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}