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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49cad0cd27f0f00304ba945e8b97084be6d1b8a9cd8680ba5268854cec0a803a' 
  AND token = 'riuf/JFwaC3aIdMeZ2Gpvd/XkSvVH+8KC4VE6uQp/LM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}