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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e14d945a43b99a766e36a210e4e65bde01963fd45fca06cab894ebc304354cfa' 
  AND token = 'E0kh2Mzwfzd2EdmxPbKOiI9spfzpUtLJupHkmKCSxOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}