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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c0d9b632090c8b00024b866ce6ef12873853bb32e627294a31e4271429a3c58' 
  AND token = 'X0eSyWNL1BZUlOeEPlbx8cJYIcTpiJqhXDb2n8WT2YA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}