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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8c94f10ca71e18f482f9e55481e8a5e6511290a5daf55150c814b1a6c7b0ad5' 
  AND token = 'TIogPbojm1WaYv2wnrjzVIQjHh5NTmGUTG1+7QWhMng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}