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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6b4077ed7edb0ba8babc847a3af9432c39a442f11ab467ec4830d39a55286c5' 
  AND token = 'uCA+w3PWPr1aJMmmCHYEMZLQ2PgHdT2/e0xiTlJXtsw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}