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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5acaafa445aca0c80b7c3e9ceb306266296edd5cc7a95ab1bd09cd479b55345b' 
  AND token = '5AHK7KixqjnX4UAyXWfTOm4wcrRGlPyLDSOwE2XNACQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}