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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd216999bf23930354f073eca5ed6077a4c0b8e4ec2255e6e5ed0f161097cf847' 
  AND token = 'CvPCRWNY01kHwYDFaOqq1EtDOL6AvpXcMaNWk0Q48KY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}