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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99fb131fb98c9e3f688910ee4bfc93c1b3626cb7e39033256f452f251f98f1c9' 
  AND token = 'uR0HpkBRso8V+aHK1UhpKbTHuBatVm81dCbwJiCxyPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}