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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2622b4d90bf21c7688f4bfc28aad962d0eec285b5cd04fca1ed2decd3bedabf' 
  AND token = 'kx3OYYYN1sdQ1Xi0oWR+Ip27V4YnnEE+tuyCaF6bYdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}