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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '633ce276cd93699d5adc848e835aeb67602d083dd2465a792b9c326c69b4bf59' 
  AND token = 'r8zr9sBjRkEX47IXsfKbUQcgqoo2KxCqQkyPjx9tGP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}