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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5b138e4b250a17c23fa14d5b66740748b3e658f4abcb3c9c012d29e0d9c5883' 
  AND token = 'zuFiNTEF1MoYdUhnVBHKRQdyuZ8BzFsSRdiKe+KAEvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}