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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f45479f63b1270c4de42556882e09ebe94a712ef84661d1344feb9460a91fe5' 
  AND token = '9OiNziyHNlf0E23LcNyOYpAuLZvUWNyZebvc1E0g9Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}