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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a9e778046578e156ada56f31f8b6eb227200713e01633290a0d38f59c44b8fa' 
  AND token = 'EPGanP1QnVdWVB45rbPHD38bjtkX6C0RtaSBj59NciA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}