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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003fbe5d9f31569c64b1bcf18d05d2bf3efc47d4908c34aa2732c32da5fc5e6f' 
  AND token = 'ltsV405/vMhDiheCDf+KI3fIiL9oG01Zcprd0utULEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}