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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e915ffd366c78bbe0f0411ff4e532921b41b16da014424af1ca9c594fbd46e' 
  AND token = 'CjlR571O5rX7gMo1qpUoRLvsUkRUEHK20wKz0k384gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}