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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '182d08ede303ea8dcbb73dd9f9243b05a93e666fe37c85ef7213ec6f1c2f2dc3' 
  AND token = 'w+zhfy33wVrOcUw74VpPpa106z/hyW40ccUmDN+DEfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}