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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a4e001c086d3c8bde73a28f9f8328ba2a2d874f3359d67f90a630222b3d3f7b' 
  AND token = '3DjA4rf+hM9XjiIkfx7c2wzoMdmASxXVIUWyIMy3MuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}