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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ee1799125b6ec8e847406cfec563b45a80b05056bdf3e98ce28fab5c8f63b6' 
  AND token = 'u7jRkUD8gkZ8DlE03gJbZoslf3t+6Es6pgKxxre06aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}