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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '814cf37b87f78eb634e1192f31985c086e1d0dee9e56984f8a33b5f983594e8a' 
  AND token = 'vBTdsPtdG5PXjuaZd8WuyJLQUd1iCWeH1zpGelMrtQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}