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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cba0da1c9d1018721f38e125b106f6a2462ea11a154add13d871f8fde45aa4df' 
  AND token = 'vU22iTCLHPifkzkgCadpVsYidkCyw7eA88qoo0+0J94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}