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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a45176fba7a2aa234019034a50129005ee6d5b046150363224ab7bf642305a9' 
  AND token = 'S13p3Si4Gki1QT40gVytoDVl9zsfFSbNI0WdnuIl95c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}