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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1c34a2a46a084885836b863d4140e3e685009bc2451a86403ac0d127dd4f83f' 
  AND token = 'MZmj4NqHnv52WMPqBmNpJOpOCSTCF5d/uwbORnUBlS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}