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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6187c190092ecf43540ba3190e0420e159e453f21fe75a0b4081983decca9d25' 
  AND token = 'GTufoHAQ/qyJI8LMmae1r4KysZjaqwYdNedr+IQmruQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}