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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fd355b72fb78c2be376ec5229fc426e7e66b414c42b4777d7e087bd931ab71' 
  AND token = 'Q8Hd88FhUOASCpgOQD/oGvEzmh1fWh3J6vOpeFXftNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}