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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a675fd657f885a514f823d5bd20c9e9b334ccdaddc28cdcecbcccbc2a69774' 
  AND token = '2/6MOWlNcj9HCfDxb6Gq8k7Acnstfb3ilZrzK9/0KUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}