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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b89c1ee7605097d972b48ede136ee044c892fdfbe276e8b776d42acbc465f2bb' 
  AND token = 'pgiEsOmlBJiqsuqnNqTAVAU7sq4p8ackyshbU08allk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}