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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13d9ce3240c677ab5da8e1336235c22d45b8bf1c42e6c5804b0a703d28c6c389' 
  AND token = 'XluJcK1It44MZ96q5dBh1AW2XuF9bPVn3U7Qm+0pyWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}