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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a90f8a1afc8d0f5138f088c17e658146b1f90326a0f7448ac0ca3ad95dd5b24f' 
  AND token = 'WIaq+P7fMwuCrvgfjUwK6UX2kaW5dN7jiFUneaO2Wc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}