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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e39f4d44826f8a8ad7c54001e491eb98f9d87ec5b8f1053be23d3e072cabe27' 
  AND token = 'cfBgaEK7kMTwl5t0H4xQ7tdMnBN99t6UNzDpa3CCDoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}