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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5430295bc9845e572e0ea01e6a062a1efbb31faacfa4cc505da63aabf3781ff3' 
  AND token = 'Gxz17GHQLij2G47T6lbyWi9N8Dbq+1Cqex/pvo5YXUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}