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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '843a6bb741f6f915f282d307b66e942f6573578199f8bdbc42e3cbc7236a2aac' 
  AND token = 'iWdrmiyPNenjhOlAo+1dchLv65CBlpn5jlOSqUyp2RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}