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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62785369bfbdd2d879e271960f9e2b04cffded66ecc9041f3b7147f93ed454c1' 
  AND token = 'Sa9SZaZ7YM+YSRA+XkYfAGe7dXa1WTv6kA2920NvSKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}