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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a47aabe65bd2dcad43d4f61442a0d36fd2cfea2c0de91994e5e4f0f0105a8c' 
  AND token = 'irwwkx3KcGqNOKvs0ZNKCVknjqnO0JVMpHx7+fx2nec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}