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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c152f2334960d58d567d4851303f53f87a912916e988cdc243d477d14926e35' 
  AND token = 'v/Bpy1oB4JFosCVfpy9PTB2BsBqdxBeAS1zOM8GBykY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}