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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6b081c19cb1c6bfe537758275cf715098b2d80d9a0aff6c1f2729571a13dca' 
  AND token = 'F+aI7d7kTbsnnOBRv5Fsqz6j6FwyacrZFPLj4nIGq9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}